EPTACOG ALFA (ACTIVATED)
About
EPTACOG ALFA (ACTIVATED) belongs to the class of antihemophilic medicine. It is primarily used to prevent excessive bleeding after surgery or other important treatments, especially in patients with congenital hemophilia who do not respond to factor VIII or IX treatment, acquired hemophilia, factor VII deficiency, and Glanzmann’s thrombosthenia.
EPTACOG ALFA (ACTIVATED) contains Eptacog alfa (activated), which is an antihemophilic drug. It helps clot the bleeding when our body’s clotting factors do not respond.
EPTACOG ALFA (ACTIVATED) may cause certain side effects such as headache, nausea, vomiting, fatigue, fever, flushing (sense of warmth) of the face, fast or irregular heart rate, low blood pressure, and redness, pain, or swelling at the injection site. These side effects may not occur in everyone using this medication and gradually resolve over time. EPTACOG ALFA (ACTIVATED) will be administered by a trained healthcare doctor.
Before starting EPTACOG ALFA (ACTIVATED), inform your doctor if you have any allergies to the components present in it. Let your doctor know about your complete medical and medication history to rule out any serious adverse effects. Inform your doctor, if you have any history of liver or kidney disease, a recent history of surgery or crush injury, atherosclerosis, or bleeding disorder. Pregnant and breastfeeding women should consult their doctor before using EPTACOG ALFA (ACTIVATED).
Uses of EPTACOG ALFA (ACTIVATED)
Medicinal Benefits
EPTACOG ALFA (ACTIVATED) is a blood coagulation medicine that helps with blood clotting. It mainly works by increasing the plasma levels of factor VIII activity in patients with hemophilia and thereby helps clot the bleeding when our body’s clotting factors do not respond.
Directions for Use
Storage
Side Effects of EPTACOG ALFA (ACTIVATED)
- Headache
- Nausea
- Vomiting
- Fatigue
- Flushing
- Fast or irregular heart rate
- Low blood pressure
- Redness, pain, or swelling at the injection site
- Blood clots in the vein and arteries
- Fever
In-Depth Precautions and Warning
Drug Warnings
To treat your condition effectively, continue receiving EPTACOG ALFA (ACTIVATED) for the period that your doctor has prescribed. Discontinue the medicine and inform your doctor if you observe any allergic reactions after receiving EPTACOG ALFA (ACTIVATED). Please consult your doctor before starting the treatment if you are pregnant, planning to conceive, or are a breastfeeding mother. EPTACOG ALFA (ACTIVATED) should be used in children only when prescribed by the doctor. This medicine may cause severe thromboembolic events. Hence, inform your doctor if you have any history of liver or kidney disease, heart problems or failure, a recent history of surgery or crush injury, atherosclerosis, thrombosis, or severe bleeding disorder. This medicine is contraindicated for patients who are allergic to mouse, hamster, or cow proteins.
Drug Interactions
Drug-Drug Interaction: EPTACOG ALFA (ACTIVATED) may interact with factor VIII products and other medicines.
Drug-Food Interaction: No interaction found.
Drug-Disease Interaction: Inform your doctor if you have liver/kidney disease, thrombosis, and severe bleeding disorders before receiving EPTACOG ALFA (ACTIVATED).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is unknown whether EPTACOG ALFA (ACTIVATED) interacts with alcohol consumption. Please consult your doctor.
Pregnancy
consult your doctorPlease inform your doctor before receiving EPTACOG ALFA (ACTIVATED) if you are pregnant.
Breast Feeding
consult your doctorThere is limited information on how EPTACOG ALFA (ACTIVATED) affects breastfeeding. If you are breastfeeding, inform your doctor before taking EPTACOG ALFA (ACTIVATED).
Driving
not applicable-
Liver
cautionIf you have a pre-existing or a history of liver disease, inform your doctor before receiving EPTACOG ALFA (ACTIVATED). Your doctor will weigh the benefits and risks before prescribing EPTACOG ALFA (ACTIVATED).
Kidney
cautionIf you have a pre-existing or a history of kidney disease, inform your doctor before receiving EPTACOG ALFA (ACTIVATED). Your doctor will weigh the benefits and risks before prescribing EPTACOG ALFA (ACTIVATED).
Children
cautionLimited information is available on the use of EPTACOG ALFA (ACTIVATED) in children. Hence, consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
- Reduce the amount of salt and protein in your diet, which will help your kidneys produce less urine.
- Avoid drinking coffee, tea, cola, energy drinks, or other caffeine sources before bedtime since it can lead to increased urination.
- Avoid activities that cause dehydration, such as excessive physical exercise or spending time in the heat.
Special Advise
- Regular monitoring of electrolytes is essential to rule out the possibility of fluid imbalance.
- Your doctor may advise liver and kidney functioning tests to monitor for hepatic and renal impairment.
- It is important to inform your doctor if you have any serious bleeding disorders.
Patients Concern
Disease/Condition Glossary
Hemophilia A: Also known as congenital hemophilia, is an inherited bleeding disorder in which the blood does not clot normally. This condition results from the birth deficit of factor VIII (useful in clotting blood). Symptoms include large or deep bruises, joint pain and swelling, and blood in urine or stool.
FAQs
EPTACOG ALFA (ACTIVATED) is used to treat Hemophilia A and Glanzmann’s thrombasthenia.
EPTACOG ALFA (ACTIVATED) contains Eptacog alfa (activated), which facilitates the clotting at the bleeding site when our body’s clotting factors do not respond.
As it is a parenteral medicine, the chance of missing the dose is less. However, if you miss a dose, consult your doctor for further instructions.
